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Sergio Grimbs

PostDoc

Sergio GrimbsCurrent project:

ColoNET: A Systems Biology Approach for Integrating Molecular Diagnostics and Targeted Therapy in Colorectal Cancer

http://www.colonet.de

 

 

 

Publications:

 

S. Bulik, S. Grimbs, C. Huthmacher, J. Selbig and H.-G. Holzhütter.  Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws – a promising method for speeding up the kinetic modelling of complex metabolic networks. FEBS Journal, Volume 276 Issue 2, Pages 410 - 424, 2009.

http://www3.interscience.wiley.com/journal/121588609/abstract

 

Z. Nikoloski, S. Grimbs, J. Selbig and O. Ebenhöh.  Hardness and Approximability of the Inverse Scope Problem. Lecture Notes in Computer Science, 5251/2008

http://www.springerlink.com/content/4780707nlt6n5113/

 

 

 

Z. Nikoloski, S. Grimbs, P. May, and J. Selbig. Metabolic Networks are NP-hard to reconstruct. J. Theo. Biol., Jul 2008. [Epub ahead of print] PMID. 18682254.

http://dx.doi.org/10.1016/j.jtbi.2008.07.015

 

S. Grimbs, J. Selbig, S. Bulik, H.-G. Holzhütter and R. Steuer. The stability and robustness of metabolic states: identifying stabilizing sites in metabolic networks. Molecular Systems Biology 3:146, Nov 2007.

http://www.nature.com/msb/journal/v3/n1/synopsis/msb4100186.html



Degree :

Diploma in Mathematics, TU Darmstadt , 2005
Diploma in Computer Science, TU Darmstadt , 2006
PhD thesis in Bioinformatics, University of Potsdam, 2009 ('Towards structure and dynamics of metabolic networks')

 

 

Contact :

Office:

Box 1.21

Phone:

+ 49 (331) 567 8626

E-mail : grimbs@mpimp-golm.mpg.de

 

 

Max-Planck-Institut für Molekulare Pflanzenphysiologie
Am Mühlenberg 1
14476 Potsdam, Germany

 

 

 

 

 

 

 

 

 

 

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